Buy 99.70% Antitumor Inhibitors Cediranib Azd2171 Recentin Raw Powder Online

  • Model NO.: CAS 55-31-2
  • Customized: Customized
  • Suitable for: Elderly, Adult
  • Purity: >99%
  • CAS: 288383-20-0
  • Products Purity: 99.70%
  • Appearance: White Powder
  • Shipping Express: EMS, TNT, UPS, DHL, FedEx
  • Packages: 10g/Aluminum Foil Bag
  • Transport Package: as Customer Specific Requests
  • Origin: HK China
  • Powder: Yes
  • Certification: GMP, HSE, ISO 9001, USP, BP, SGS
  • State: Solid
  • Cediranib: Potent Inhibitor of Vascular Endothelial Growth
  • Export: in Global
  • MW: 450.5
  • Delivery Time: 3 to 6 Days
  • Payment Methods: Western Union, T/T, Bitcoins, Moneygram
  • Trademark: SGS ISO9001
  • Specification: 99.70%
  • HS Code: 3001
Buy 99.70% Antitumor Inhibitors Cediranib AZD2171 Recentin Raw Powder Online 

Quick Details of Cediranib
Name: Cediranib 
CAS#: 288383-20-0
Chemical Formula: C25H27FN4O3 
Exact Mass: 450.20672 
Molecular Weight: 450.5 
Elemental Analysis: C, 66.65; H, 6.04; F, 4.22; N, 12.44; O, 10.65.
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Cediranib of COA
Item Specification
Specific rotation +39.5 to +41.5°
State of solution(transmittance) Clear 98.0% min.
Chloride[cl] 0.020% max.
Ammonium [NH4] 0.02% max.
Sulfate[SO4] 0.020% max
Iron[Fe] 10ppm max.
Heavy metals [Pb] 10ppm max
Arsenic[As2O3] 1ppm max
Other amino acids Chromatographically not detectable
Loss on drying 0.20% max.
Residue on ignition[sulfated] 0.10% max.
Assay 99.70% min

What is Cediranib
Cediranib is a new drug that researchers are investigating. It is pronounced sed-ih-ran-ib. It is also called Recentin or AZD2171.Cediranib is a type of biological therapy called a tyrosine kinase inhibitor (TKI). Tyrosine kinases are proteins that cells use to signal to each other. They act as chemical messengers for the cells to tell each other to grow and develop.Cediranib blocks signals telling cancer cells to make blood vessels. If they can't grow blood vessels, cancer cells can't get the nutrients they need and so the cancer cannot grow. Drugs that stop (inhibit) blood vessels forming are called angiogenesis
inhibitors.Cediranib is a tablet that you take once a day. Researchers have tested it in trials with chemotherapy and on its own. what are the benifits of Cediranib
Cediranib even suppresses tubule sprouting at subnanomolar concentrations and inhibits VEGF-induced angiogenesis. Cediranib causes hypertrophy in bone growth plate and prevents luteal development in ovary. These are physiological processes that are dependent upon angiogenesis. Cediranib shows broad spectrum activity in human tumor models at doses that are well tolerated. Besides,
Cediranib causes regression of vascular tissues in human lung tumor xenografts.

Cediranib Applications
Cediranib inhibition of bFGF and EGF when an IC50 of 0.5 and 0.11 μM. In the MG63 cell lines, Cediranib inhibiting PDGF-AA, IC50 of 0.04 μM. Cediranib Flt-1 associated kinase inhibition, IC50 of 5 nM,Cediranib inhibition of VEGF-C and VEGF-D receptor Flt-4, IC50 of less than 3 nM. In addition, cediranib inhibition of c-Kit and PDGFR-β tyrosine kinase, IC50 were 2 and 5 nM. In vitro, micromolar concentrations cediranib can directly inhibit the proliferation of tumor cells.




 

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