Research says diabetics are expected to get rid of insulin dependence

Release date: 2007-05-17

Research says diabetics are hoping to get rid of insulin dependence 13 Brazilian patients with type 1 diabetes have recently been ecstatic, because with a new type of stem cell transplant therapy, they don't have to rely on insulin or any other drugs to sustain their lives. The Journal of the American Medical Association published a research report on the 10th, claiming a breakthrough in the treatment of diabetes. Medical staff conducted a stem cell transplant experiment in 15 patients with type 1 diabetes in Brazil. As a result, 13 patients have shed their dependence on insulin at this stage and do not need to take other drugs. The first patient to undergo an experiment had not been given artificial insulin for 3 years. As one of the two clinical types of diabetes, type 1 diabetes is an autoimmune disease caused by the human immune system destroying cells that produce insulin in the pancreas as foreign cells. It is not as common as type 2 diabetes, but patients must rely on insulin for life to sustain their lives. Dr. Richard Burt, a senior research author at the Northwestern University School of Medicine in Chicago, said that although stem cell transplantation has not yet matured as a treatment, "this is the first in the history of treatment for type 1 diabetes." After achieving this result, the patient does not need any medication ... or any treatment, the blood sugar concentration remains normal." Although according to the researchers, there was a “potential risk of life” in this experiment, none of the 15 patients who underwent the experiment died, and there were no persistent side effects. Bert said that after the approval of the Brazilian Ethics Committee, they conducted the experiment at the bone marrow center of the University of Sao Paulo, Brazil. The 15 subjects were between the ages of 14 and 31 and were just diagnosed with type 1 diabetes soon. He said that this time is critical because the cells that produce insulin in the patient are not completely damaged by the immune system. Burt said that the patient was hospitalized for about three weeks. Many patients have nausea, vomiting and hair loss due to the side effects of the therapy during the experiment. However, the side effects did not last long. Some questions have been raised about the potential risks of this new stem cell transplant therapy. For example, some medical personnel believe that this experiment should not be conducted for 14-year-old children. Researchers say they also need to conduct further research on stem cell transplant therapy to determine if it can be a universal treatment for type 1 diabetes. Although stem cell therapy has not yet matured, its breakthrough in the treatment of diabetes still causes vibration in the medical community. Medical staff are very optimistic about its prospects.
—— Information from: Meditech Medical Network

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