Release date: 2014-12-30
Scientists use microscopic images to reveal how proteins that bind cells together are cut off in lung cancer cells so that cancer cells can rush out of the "encirclement" and spread, and research is published in Cell Reports.
Researchers at the Manchester Cancer Institute in the United Kingdom have found that cancer cells spread when the bonds that bind to cancer cells (controlled by a protein called Tiam 1) are "chopped". Healthy cells routinely kill old cell residues so that they can be broken down and recycled again, but this process is out of control in lung cancer cells.
For this cycle, the spread of lung cancer can be stopped by blocking the cells firmly together. Researcher Dr. ANGELIKI Malliri said: This important study shows for the first time how lung cancer cells sever the relationship with neighboring cells by hijacking the cell recycling cycle and begin to spread throughout the body. The drawback of recycling cycles can help stop the spread of lung cancer.
In the UK, there are nearly 43,500 new cases of lung cancer each year. It is the most common cause of cancer deaths, killing more than 35,000 people each year in the UK. In the UK, lung cancer causes more than one-fifth of cancer deaths, and it is crucial to find effective new therapies to fight the disease and save more lives. As with earlier studies, it is important to find treatment that can block the spread of cancer cells one day.
Source: Bio Valley
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