How to use foot-and-mouth disease vaccine

The vaccines for prevention of foot-and-mouth disease include cattle O-type foot-and-mouth disease inactivated vaccine, pig O-type foot-and-mouth disease inactivated vaccine, and cattle and sheep foot-and-mouth disease O-type ratification attenuated vaccine. Its specific application is:

(1) The inactivated vaccine against O-type foot-and-mouth disease of cattle is selected as a virulent strain with a broad antigenic spectrum, antigenicity, and immunogenicity, and is inoculated into a monolayer culture of BHK-21 subcultured cell lines to prepare viral antigens. Diethylenimine (BEI) was inactivated and a cream vaccine made with mineral oil adjuvant was used. For a slightly pink or milky viscous liquid. It is used for vaccination and emergency vaccination of cattle, buffalo, cows and yaks of various ages and has an immunization duration of 6 months. Adult beef was intramuscularly injected with 3 ml and 2 ml of intramuscular yak under 1 year old. This product should prevent freezing. Stored at 4-8°C for a period of 10 months.

(2) Inactivated swine O-type foot-and-mouth disease vaccine is inoculated with virulent swine virus to inoculate BHK-21 or IBRS-2 cell monolayers, and the cytotoxic broth is harvested, inactivated by diethyleneimine (BEI), and emulsified with oil adjuvant. to make. Milky white or light red viscous emulsion, after storage allows a small amount of oil on the liquid surface, there is a trace of water at the bottom of the bottle (not more than 1/10, respectively), and the shake is a homogeneous emulsion. It is used to prevent swine type O foot-and-mouth disease. The duration of immunity is 6 months. Shake well before vaccination, intramuscular injection of pig ear, body weight 10 ~ 25 kg 2 ml injection; 25 kg more than 3 ml injection. Note that the vaccine should be shipped in refrigerated packaging below 10°C. This product is stored in a cold storage at 2 to 10°C and is valid for 1 year.

(3) Foot-and-mouth disease O-type mouse attenuated live attenuated vaccines were obtained by inoculating lactating rabbits with O-type murine attenuated strains of foot-and-mouth disease. The toxic tissues were harvested and ground, and the virus leaching solution was added with the same amount of glycerol. Dark red liquid. After standing, some of the bottom of the bottle precipitated; after shaking, it was a uniform suspension. It is used to prevent O-type foot-and-mouth disease in cattle, yaks and goats over 4 months old and over 4 months old. Intramuscular injection of 2 ml of cattle, 1 ml of sheep subcutaneous injection, immunity duration of 6 to 8 months. This product can not be used for pigs, cows, buffaloes. Stored at -12°C and below, valid for 1 year; stored at 2~6°C for 5 months; stored at 20~22°C for 7 days.

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Imported French lens

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