Elevated homocysteine ​​is an accomplice to hypertensive stroke

Chinese people with high blood pressure have a big accomplice - Peking University* Hospital and Anhui Medical University Anhui Institute of Biomedical Research have proved that homocysteine ​​(Hcy) and hypertension can make strokes happen. The risk is 12 times that of healthy people.

Hypertension is an important risk factor for cerebral hemorrhage and cerebral infarction. However, there are many factors outside of it that are also related to stroke, such as high blood sugar, high blood fat, smoking, drinking, and obesity. Recent medical research has confirmed that there is a close relationship between elevated Hcy and stroke. Hcy is an intermediate product of methionine in the metabolism of human cells. When it exceeds a certain concentration in human blood, it will damage small blood vessel endothelial cells, aggravate the blood coagulation process, cause thrombosis, and bring fatal to small blood vessel-intensive brain. Threat.

The collaborative research between Peking University* Hospital and Anhui Medical College of Anhui Province was completed in 12 years from 1995 to 2006. The study cohort of 39,165 people was prospectively tracked for an average of more than 6 years. Studies have shown that in patients with hypertension or hyperhomocysteinemia alone, the risk of stroke death is 3 times and 4 times that of the normal population, respectively, while the risk of stroke is increased to 12 with elevated blood pressure and high Hcyemia. Times. Obviously, elevated Hcy is an accomplice to high blood pressure leading to stroke and should be given special attention.

The current annual incidence of stroke in China has reached 250/100,000. At the symposium held by the "Health Times" and other "Control of Hypertension and Prevention of Stroke", experts at the meeting believed that Hcy should be regarded as one of the important reasons for the high incidence of stroke in China. Because Hcy and hypertension have significant synergistic effects on stroke events, simultaneous control of these two is an important measure to effectively prevent and control the high incidence of stroke in China.

Professor Huo Yong, director of the Department of Cardiology at Peking University* Hospital, pointed out that the safe and effective way to reduce Hcyzui is to supplement folic acid. Liu Lisheng, chairman of the World Hypertension League and a professor at Fuwai Hospital of the Chinese Academy of Medical Sciences, pointed out that according to the concept of joint control of multiple risk factors, it is recommended that the health and drug supervision departments of China support the development and clinical application of compound drugs for simultaneous control of blood pressure and Hcy. In order to improve the long-term treatment compliance of hypertensive patients, the incidence and mortality of strokes ranked in the first cause of death in China are reduced.

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